Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allele substitution of the streptokinase gene reduces the nephritogenic capacity of group A streptococcal strain NZ131.

Infection and immunity - 1 Mar 2000

Nordstrand A, McShan W M, Ferretti J J, Holm S E, Norgren M

Abstract excerpt

To investigate the role of allelic variants of streptokinase in the pathogenesis of acute poststreptococcal glomerulonephritis (APSGN), site-specific integration plasmids were constructed, which contained either the non-nephritis-associated streptokinase gene (skc5) from the group C streptococcal strain Streptococcus equisimilis H46A or the nephritis-associated streptokinase gene (ska1) from the group A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Complement C3
Share to Glomerulonephritis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

Share to Plasmids

Share to Streptococcal Infections

Share to Streptococcus pyogenes

Source

Open in PubMed Open full text

Identifiers

PMID: 10678902
DOI: 10.1128/IAI.68.3.1019-1025.2000
PMCID: PMC97243

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allele substitution of the streptokinase gene reduces the nephritogenic capacity of group A streptococcal strain NZ131.PMID 10678902Read ↗

Genome sequence of a Lancefield group C Streptococcus zooepidemicus strain causing epidemic nephritis: new information about an old disease.Semantic proximity Read ↗

Streptokinase alleles and disease association in group A streptococci.Semantic proximity Read ↗

Improved transformation efficiency of group A Streptococcus by inactivation of a type I restriction modification system.Semantic proximity Read ↗

Streptokinase gene polymorphism in group A streptococci isolated from Ethiopian children with various disease manifestations.Semantic proximity Read ↗

Improved transformation efficiency of group A <i>Streptococcus</i> by inactivation of a type I restriction modification systemSemantic proximity Read ↗

Plasminogen Is a Critical Host Pathogenicity Factor for Group A Streptococcal InfectionSemantic proximity Read ↗

Streptokinase activity among group A streptococci in relation to streptokinase genotype, plasminogen binding, and disease manifestations.Semantic proximity Read ↗

Characterization of allelic replacement in Streptococcus parasanguis: transformation and homologous recombination in a 'nontransformable' streptococcus.Semantic proximity Read ↗

Genetic mutation of recombination activating gene 1 in Dahl salt-sensitive rats attenuates hypertension and renal damage.Semantic proximity Read ↗

Dual Control of Streptokinase and Streptolysin S Production by thecovRSandfasCAXTwo-Component Regulators inStreptococcus dysgalactiaesubsp.equisimilisSemantic proximity Read ↗

Myocardial tissue damage in rabbits injected with group A streptococci, types M1 and M22. Role of bacterial immunoglobulin G-binding surface proteins.Semantic proximity Read ↗

Immune complex binding Streptococcus pyogenes type M12/emm12 in experimental glomerulonephritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.