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Article

Streptokinase activity among group A streptococci in relation to streptokinase genotype, plasminogen binding, and disease manifestations.

Microbial pathogenesis - 1 Jan 1995

Tewodros W, Norgren M, Kronvall G

Abstract excerpt

Certain genotypic variants of streptokinase (ska) of beta-hemolytic streptococci group A have been associated with acute post-streptococcal glomerulonephritis (APSGN). In our earlier studies on strains isolated from Ethiopian children with various streptococcal disease manifestation, we reported an even distribution of streptokinase genotypes with no association to disease patterns. Considering the possibility...

Topics

Adolescent
Amino Acid Sequence
Child
Child, Preschool
Enzyme Activation
Genetic Variation
Genotype
Glomerulonephritis
Humans
Molecular Sequence Data
Plasminogen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Binding

Streptococcal Infections

Streptococcus pyogenes

Streptokinase

Source

Identifiers

PMID: 7783598
DOI: 10.1016/s0882-4010(05)80012-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7783598-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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