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Article

Lack of association of the alpha2-macroglobulin locus on chromosome 12 in AD.

Neurology - 25 Jan 2000

Gibson A M, Singleton A B, Smith G, Woodward R, McKeith I G, Perry R H, Ince P G, Ballard C G, Edwardson J A, Morris C M

Abstract excerpt

OBJECTIVE: Analysis of AD has revealed that the apolipoprotein E locus (APOE) cannot account for all of the genetic risk associated with AD. Whole genome scanning in AD families suggests that a chromosome 12 locus may contribute significantly to disease development. The alpha2-macroglobulin gene (A2M) has been suggested as a candidate locus for AD based on analysis of familial AD. METHOD: We determined, in 195...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10668708
DOI: 10.1212/wnl.54.2.433

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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