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Article

Cholinergic dysfunction in diseases with Lewy bodies.

Neurology - 25 Jan 2000

Tiraboschi P, Hansen L A, Alford M, Sabbagh M N, Schoos B, Masliah E, Thal L J, Corey-Bloom J

Abstract excerpt

OBJECTIVE: To evaluate cholinergic activity in diseases with Lewy bodies (LB; LB variant of AD [LBV], diffuse LB disease [DLBD], and Parkinson's disease [PD]) to determine if 1) AD changes are requisite to cholinergic dysfunction, 2) cholinergic activity declines to the same extent in neocortical and archicortical areas, and 3) cholinergic loss is influenced by APOE genotype. BACKGROUND: Like AD, diseases with LB...

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Source

Identifiers

PMID: 10668703
DOI: 10.1212/wnl.54.2.407

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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