Article
Polymorphism of the renalase gene in end-stage renal disease patients affected by hypertension.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Nov 2012
Stec Anna, Semczuk Andrzej, Furmaga Jacek, Ksiazek Andrzej, Buraczynska Monika
Abstract excerpt
BACKGROUND: Renalase is a novel flavin adenine dinucleotide-dependent amine oxidase that is secreted by the kidney. It circulates in the blood and modulates the cardiac function and systemic blood pressure. Insufficiency of renalase in patients with chronic kidney disease may explain the frequent occurrence of hypertension among patients with end-stage renal disease (ESRD) and an increased risk of cardiovascular...
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