Article
An MboI two-allele polymorphism may implicate the human renin gene in primary hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Sept 1998
Frossard P M, Lestringant G G, Elshahat Y I, John A, Obineche E N
Abstract excerpt
As a key enzyme of the renin-angiotensin-aldosterone system, the renin gene (REN) is a good candidate quantitative trait locus that may be implicated in the molecular etiology of essential hypertension. Among mixed reports on the subject, a REN MboI restriction fragment length polymorphism has be...
Topics
- Aging
- Alleles
- Body Mass Index
- Cholesterol
- DNA
- Female
- Humans
- Hypertension
- Male
- Middle Aged
- Polymorphism, Genetic
- Quantitative Trait, Heritable
- Renin
- Reverse Transcriptase Polymerase Chain Reaction
- Sex Characteristics
- Site-Specific DNA-Methyltransferase (Adenine-Specific)
- United Arab Emirates