Article
Lack of Bcl10 mutations in malignant cartilaginous tumors.
International journal of molecular medicine - 1 Mar 2002
Park Yong-Koo, Park Hye-Rim, Kim Youn-Wha, Chi Sung-Gil, Unni K Krishnan
Abstract excerpt
The Bcl10 gene was recently isolated from the breakpoint region of t(1;14)(p22;q32) in mucosa-associated lymphoid tissue (MALT) lymphomas. Somatic mutations of Bcl10 were found in not only t(1;14)-bearing MALT lymphomas, but also a wide range of other tumors. To clarify the actual frequency and spectrum of Bcl10 mutations in primary malignant chondrogenic tumors, we examined 89 cases of malignant chondrogenic...
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