Article
Bcl10 expression, rearrangement and mutation in MALT lymphoma: correlation with expression of nuclear factor-kappaB.
International journal of oncology - 1 Aug 2001
Ohshima K, Muta H, Kawasaki C, Muta K, Deyev V, Kanda M, Kumano Y, Podack E R, Kikuchi M
Abstract excerpt
Mucosa-associated lymphoid tissue (MALT) lymphomas usually involve extranodal sites, especially the stomach, lung and salivary glands. The Bcl10 gene was recently isolated from the breakpoint region of t(1;14) (p22;q32) in MALT lymphomas, and considered to be an apoptosis-associated gene, and involves a caspase recruitment domain (CARD)-containing protein that activates NF-kappaB. We investigated the role of...
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