Article
Alcohol deprivation effect is prolonged in the alcohol preferring (P) rat after repeated deprivations.
Alcoholism, clinical and experimental research - 1 Jan 2000
Rodd-Henricks Z A, McKinzie D L, Shaikh S R, Murphy J M, McBride W J, Lumeng L, Li T K
Abstract excerpt
BACKGROUND: The alcohol deprivation effect (ADE) is a temporary increase in the ratio of ethanol/total fluid intake and the voluntary intake of ethanol solutions over baseline drinking conditions when ethanol access is reinstated after a period of alcohol deprivation. The ADE has been posited to be an animal model for alcohol craving. The current study examined the effects of initial deprivation length and number...
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