Article
Is the alcohol deprivation effect genetically mediated? Studies with HXB/BXH recombinant inbred rat strains.
Alcoholism, clinical and experimental research - 1 Jul 2014
Vanderlinden Lauren A, Saba Laura M, Printz Morton P, Flodman Pamela, Koob George, Richardson Heather N, Hoffman Paula L, Tabakoff Boris
Abstract excerpt
BACKGROUND: Two features of alcohol addiction that have been widely studied in animal models are relapse drinking following periods of alcohol abstinence and the escalation of alcohol consumption after chronic continuous or intermittent alcohol exposure. The genetic contribution to these phenotypes has not been systematically investigated. METHODS: HXB/BXH recombinant inbred (RI) rat strains were given access to...
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