Article
Repeated cycles of binge-like ethanol (EtOH)-drinking in male C57BL/6J mice augments subsequent voluntary EtOH intake but not other dependence-like phenotypes.
Alcoholism, clinical and experimental research - 1 Oct 2013
Cox Benjamin R, Olney Jeffrey J, Lowery-Gionta Emily G, Sprow Gretchen M, Rinker Jennifer A, Navarro Montserrat, Kash Thomas L, Thiele Todd E
Abstract excerpt
BACKGROUND: Recently, procedures have been developed to model specific facets of human alcohol abuse disorders, including those that model excessive binge-like drinking (i.e., "drinking-in-the-dark," or DID procedures) and excessive dependence-like drinking (i.e., intermittent ethanol [EtOH] vapor exposure). Similar neuropeptide systems modulate excessive EtOH drinking stemming from both procedures, raising the...
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