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Article

6-OHDA-lesions of the nucleus accumbens disrupt the acquisition but not the maintenance of ethanol consumption in the alcohol-preferring P line of rats.

Alcoholism, clinical and experimental research - 1 Sept 1997

Ikemoto S, McBride W J, Murphy J M, Lumeng L, Li T K

Abstract excerpt

The aim of the present study was to determine whether reduction of dopamine (DA) innervation to the nucleus accumbens (ACB) alters the maintenance and/or acquisition of ethanol drinking in female alcohol-preferring P rats. Compared with sham-lesioned animals, bilateral microinjections of 6-OHDA (12 micrograms/2.4 microliters/site) into the ACB did not alter the consumption of 10% ethanol in rats that had prior...

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PMID: 9309315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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