Article
Postdependent state in rats as a model for medication development in alcoholism.
Addiction biology - 1 Jan 2015
Meinhardt Marcus W, Sommer Wolfgang H
Abstract excerpt
Rational development of novel therapeutic strategies for alcoholism requires understanding of its underlying neurobiology and pathophysiology. Obtaining this knowledge largely relies on animal studies. Thus, choosing the appropriate animal model is one of the most critical steps in pre-clinical medication development. Among the range of animal models that have been used to investigate excessive alcohol...
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