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Article

The discovery of single-nucleotide polymorphisms--and inferences about human demographic history.

American journal of human genetics - 1 Dec 2001

Wakeley J, Nielsen R, Liu-Cordero S N, Ardlie K

Abstract excerpt

A method of historical inference that accounts for ascertainment bias is developed and applied to single-nucleotide polymorphism (SNP) data in humans. The data consist of 84 short fragments of the genome that were selected, from three recent SNP surveys, to contain at least two polymorphisms in their respective ascertainment samples and that were then fully resequenced in 47 globally distributed individuals....

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Identifiers

PMID: 11704929
DOI: 10.1086/324521
PMCID: PMC1235544

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