Article
New explicit expressions for relative frequencies of single-nucleotide polymorphisms with application to statistical inference on population growth.
Genetics - 1 Sept 2003
Polanski A, Kimmel M
Abstract excerpt
We present new methodology for calculating sampling distributions of single-nucleotide polymorphism (SNP) frequencies in populations with time-varying size. Our approach is based on deriving analytical expressions for frequencies of SNPs. Analytical expressions allow for computations that are faster and more accurate than Monte Carlo simulations. In contrast to other articles showing analytical formulas for...
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