Article
Robust demographic inference from genomic and SNP data.
PLoS genetics - 1 Oct 2013
Excoffier Laurent, Dupanloup Isabelle, Huerta-Sánchez Emilia, Sousa Vitor C, Foll Matthieu
Abstract excerpt
We introduce a flexible and robust simulation-based framework to infer demographic parameters from the site frequency spectrum (SFS) computed on large genomic datasets. We show that our composite-likelihood approach allows one to study evolutionary models of arbitrary complexity, which cannot be tackled by other current likelihood-based methods. For simple scenarios, our approach compares favorably in terms of...
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