Article
A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle.
Genes & development - 15 Jan 2000
Blixt A, Mahlapuu M, Aitola M, Pelto-Huikko M, Enerbäck S, Carlsson P
Abstract excerpt
In the mouse mutant dysgenetic lens (dyl) the lens vesicle fails to separate from the ectoderm, causing a fusion between the lens and the cornea. Lack of a proliferating anterior lens epithelium leads to absence of secondary lens fibers and a dysplastic, cataractic lens. We report the cloning of...
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