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Article

Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage.

Developmental biology - 1 Feb 2007

Blixt Asa, Landgren Henrik, Johansson Bengt R, Carlsson Peter

Abstract excerpt

The dysgenetic lens (dyl) mouse mutant has mutations in Foxe3, which inactivate DNA binding by the encoded forkhead transcription factor. Here we confirm, by targeted inactivation, that Foxe3 mutations are responsible for the dyl phenotype, which include loss of lens epithelium; a small, cataract...

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Share to Anterior Eye Segment
Share to Eye Proteins
Share to Forkhead Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lens, Crystalline

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Share to Paired Box Transcription Factors

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Source

Identifiers

PMID: 17064680
DOI: 10.1016/j.ydbio.2006.09.021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17064680-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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