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Article

Mutations in the human forkhead transcription factor FOXE3 associated with anterior segment ocular dysgenesis and cataracts.

Human molecular genetics - 1 Feb 2001

Semina E V, Brownell I, Mintz-Hittner H A, Murray J C, Jamrich M

Abstract excerpt

Dysgenesis of the anterior segment of the eye delineates a spectrum of human developmental disorders that show wide phenotypic and genetic heterogeneity. It is also frequently associated with cataracts and glaucoma resulting in visual disability in childhood. The recently described forkhead transcription factor gene Foxe3 was shown to be involved in the dysgenetic lens phenotype in mice, which is characterized by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forkhead Transcription Factors

Share to Frameshift Mutation

Share to Lens, Crystalline

Share to Mutagenesis, Insertional

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Source

Identifiers

PMID: 11159941
DOI: 10.1093/hmg/10.3.231

Genes

FOXE3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Mutations in the human forkhead transcription factor FOXE3 associated with anterior segment ocular dysgenesis and cataracts.PMID 11159941Read ↗

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