Article
Receptor tyrosine phosphatases are required for motor axon guidance in the Drosophila embryo.
Cell - 23 Feb 1996
Desai C J, Gindhart J G, Goldstein L S, Zinn K
Abstract excerpt
The receptor tyrosine phosphatases DPTP69D and DPTP99A are expressed on motor axons in Drosophila embryos. In mutant embryos lacking DPTP69D protein, motor neuron growth cones stop growing before reaching their muscle targets, or follow incorrect pathways that bypass these muscles. Mutant embryos lacking DPTP99A are indistinguishable from wild type. Motor axon defects in dptp69D dptp99A double mutant embryos,...
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