Article
Complex genetic interactions among four receptor tyrosine phosphatases regulate axon guidance in Drosophila.
Molecular and cellular neurosciences - 1 Feb 2001
Sun Q, Schindelholz B, Knirr M, Schmid A, Zinn K
Abstract excerpt
Four receptor-linked protein tyrosine phosphatases are selectively expressed on central nervous system axons in the Drosophila embryo. Published data show that three of these (DLAR, DPTP69D, DPTP99A) regulate motor axon guidance decisions during embryonic development. Here we examine the role of the fourth neural phosphatase, DPTP10D, by analyzing double-, triple-, and quadruple-mutant embryos lacking all...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
