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Article

Dopamine D3 receptor gene polymorphism and response to clozapine in schizophrenic Pakastani patients.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Dec 1999

Scharfetter J, Chaudhry H R, Hornik K, Fuchs K, Sieghart W, Kasper S, Aschauer H N

Abstract excerpt

The dopamine D3 receptor (DRD3) appears to play an important role in the mediation of antipsychotic drug action. Genetic association of treatment response to the atypical antipsychotic drug clozapine with the DRD3 polymorphism Ser9Gly was investigated in a sample of 32 schizophrenic patients. We found association of treatment response with allele Gly-9 (P=0.0058) and with genotypes consisting of Gly-9 (P=0.033)...

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Source

Identifiers

PMID: 10647091
DOI: 10.1016/s0924-977x(99)00044-9

Genes

DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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