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Article

Autocrine regulation of collagenase 3 (matrix metalloproteinase 13) during osteoarthritis.

Arthritis and rheumatism - 1 Jan 2000

Shlopov B V, Gumanovskaya M L, Hasty K A

Abstract excerpt

OBJECTIVE: To correlate the increased collagenase production previously seen in chondrocytes isolated from osteoarthritic (OA) lesions and the expression of cytokines and cytokine receptors. METHODS: Chondrocytes were isolated from OA cartilage and characterized for synthesis of collagenases, cytokines, and cytokine receptors by Northern and Western blot analyses, RNA protection assay, and flow cytometry....

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PMID: 10643716
DOI: 10.1002/1529-0131(200001)43:1<195::AID-ANR24>3.0.CO;2-G

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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