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Article

Expression profiling of metalloproteinases and their inhibitors in cartilage

1 Jan 2004

Abstract excerpt

OBJECTIVE: To profile the expression of all known members of the matrix metalloproteinase (MMP), ADAMTS, and tissue inhibitor of metalloproteinases (TIMP) gene families in normal cartilage and cartilage from patients with osteoarthritis (OA). METHODS: Human cartilage was obtained from femoral heads at joint replacement for OA or following fracture to the femoral neck. Total RNA was purified, and gene expression...

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PMID: 14730609
DOI: 10.1002/art.11433

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