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Article

Ovine uterine gland knock-out model: effects of gland ablation on the estrous cycle.

Biology of reproduction - 1 Feb 2000

Allison Gray C, Bartol F F, Taylor K M, Wiley A A, Ramsey W S, Ott T L, Bazer F W, Spencer T E

Abstract excerpt

Ovine endometrial gland development is a postnatal event that can be inhibited epigenetically by chronic exposure of ewe lambs to a synthetic progestin from birth to puberty. As adults, these neonatally progestin-treated ewes lack endometrial glands and display a uterine gland knockout (UGKO) phenotype that is useful as a model for study of endometrial function. Here, objectives were to determine: 1) length of...

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PMID: 10642586
DOI: 10.1095/biolreprod62.2.448

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PGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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