Article
A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons.
Genes & development - 1 Jan 2000
Fode C, Ma Q, Casarosa S, Ang S L, Anderson D J, Guillemot F
Abstract excerpt
Neurogenin1 (Ngn1), Neurogenin2 (Ngn2), and Mash1 encode bHLH transcription factors with neuronal determination functions. In the telencephalon, the Ngns and Mash1 are expressed at high levels in complementary dorsal and ventral domains, respectively. We found that Ngn function is required to maintain these two separate expression domains, as Mash1 expression is up-regulated in the dorsal telencephalon of Ngn...
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