Article
AlphaMUPA mice: a transgenic model for increased life span.
Neurobiology of aging - 1 Jan 2000
Miskin R, Masos T, Yahav S, Shinder D, Globerson A
Abstract excerpt
AlphaMUPA is a line of transgenic mice that, compared with their wild type (WT) counterparts, spontaneously eat less (approximately 20%) and live longer (average approximately 20%), thus resembling dietary-restricted (DR) mice. Here, we show that body temperature was significantly reduced in alphaMUPA compared with WT throughout a wide range of ages. Plasma corticosterone was significantly higher in young...
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