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AlphaMUPA mice: a transgenic model for longevity induced by caloric restriction.

Mechanisms of ageing and development - 1 Feb 2005

Miskin Ruth, Tirosh Oren, Pardo Michal, Zusman Igor, Schwartz Betty, Yahav Shlomo, Dubnov Gal, Kohen Ron

Abstract excerpt

Caloric restriction (CR) is currently the only therapeutic intervention known to attenuate aging in mammals, but the underlying mechanisms of this phenomenon are still poorly understood. To get more insight into these mechanisms, we took advantage of the alphaMUPA transgenic mice that previously were reported to spontaneously eat less and live longer compared with their wild-type control mice. Currently, two...

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Identifiers

PMID: 15621205
DOI: 10.1016/j.mad.2004.08.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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