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Article

AMY plaques in familial AD: comparison with sporadic Alzheimer's disease.

Neurology - 11 Jan 2000

Lippa C F, Schmidt M L, Nee L E, Bird T, Nochlin D, Hulette C, Mori H, Lee V M, Trojanowski J Q

Abstract excerpt

OBJECTIVE: To assess AMY expression in familial AD (FAD). BACKGROUND: The discovery of nonbeta-amyloid (Abeta), plaque-like deposits composed of a 100-kd protein (AMY) in sporadic AD (SAD) brains prompted us to determine whether these plaques (AMY plaques) also occur in AD due to mutations of the presenilin-1 (PS-1), presenilin-2 (PS-2), or the amyloid precursor protein (APP) genes. METHODS: We used...

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PMID: 10636133
DOI: 10.1212/wnl.54.1.100

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APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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