Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Antibodies from HIV-positive and AIDS patients bind to an HIV envelope multivalent vaccine.

Journal of acquired immune deficiency syndromes (1999) - 1 Dec 1999

Carlos M P, Yamamura Y, Díaz-Mitoma F, Torres J V

Abstract excerpt

A major problem impeding development of an effective HIV vaccine is the rapid antigenic variability that is characteristic of several envelope glycoprotein epitopes. Frequent mutations alter the composition of the most immunogenic regions of the envelope glycoprotein. We have prepared a synthetic immunogen representing the evolution of the major hypervariable epitopes on the envelope glycoprotein (gp120) of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acquired Immunodeficiency Syndrome
Share to AIDS Vaccines

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epitopes

Share to HIV Antibodies

Share to HIV Envelope Protein gp120

Share to HIV Infections

Share to Peptide Fragments

Share to Vaccines, Synthetic

Source

Identifiers

PMID: 10634192
DOI: 10.1097/00126334-199912010-00001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Antibodies from HIV-positive and AIDS patients bind to an HIV envelope multivalent vaccine.PMID 10634192Read ↗

HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees.Semantic proximity Read ↗

Viral sequence diversity: challenges for AIDS vaccine designsSemantic proximity Read ↗

A critical question for HIV vaccine development: which antibodies to induce?Semantic proximity Read ↗

Peptide immunogens designed to enhance immune responses against human immunodeficiency virus (HIV) mutant strains: a plausible means of preventing viral persistence.Semantic proximity Read ↗

Challenges in the design of a T cell vaccine in the context of HIV-1 diversity.Semantic proximity Read ↗

Design of immunogens to elicit broadly neutralizing antibodies against HIV targeting the CD4 binding site.Semantic proximity Read ↗

Immunoreactivity of intact virions of human immunodeficiency virus type 1 (HIV-1) reveals the existence of fewer HIV-1 immunotypes than genotypes.Semantic proximity Read ↗

Candidate vaccine sequences to represent intra- and inter-clade HIV-1 variation.Semantic proximity Read ↗

Bioorganic approaches towards HIV vaccine design.Semantic proximity Read ↗

Correlations between HIV-1 clades and HIV-1 antibody neutralization sensitivity: significant for vaccine development?Semantic proximity Read ↗

Synthetic vaccines and HIV-1 hypervariability: a "mixotope" approach.Semantic proximity Read ↗

Genetic variation of HIV type 1: relevance of interclade variation to vaccine development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.