Article
Bioorganic approaches towards HIV vaccine design.
Current pharmaceutical design - 1 Jan 2003
Wang Lai-Xi
Abstract excerpt
The worldwide epidemic of HIV/AIDS urges the development of an effective vaccine. With the identification of HIV as the cause of AIDS about two decades ago, it was once expected that a preventive vaccine would follow closely behind. But the early promise of HIV envelope gp120 as a preventive vaccine was not fulfilled. Broadly neutralizing antibodies and HIV-specific cytotoxic T lymphocytes (CTL) are two immune...
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