Article
Development of melanocyte progenitors in murine Steel mutant neural crest explants cultured with stem cell factor, endothelin-3, or TPA.
Pigment cell research - 1 Oct 1998
Ono H, Kawa Y, Asano M, Ito M, Takano A, Kubota Y, Matsumoto J, Mizoguchi M
Abstract excerpt
Stem cell factor (SCF) has been suggested to be indispensable for the development of neural crest cells into melanocytes because Steel mutant mice (i.e., Sl/Sl(d)) have no pigmented hairs. On the other hand, it has been demonstrated that the addition of endothelin 3 (ET-3) or TPA to neural crest...
Topics
- Animals
- Cholera Toxin
- Culture Techniques
- Dihydroxyphenylalanine
- Endothelin-3
- Genotype
- Immunohistochemistry
- Melanocytes
- Mice
- Muridae
- Mutation
- Neural Crest
- Proto-Oncogene Proteins c-kit
- Stem Cell Factor
- Stem Cells
- Tetradecanoylphorbol Acetate
- Tissue Distribution