Non-unity molecular heritability demonstrated by continuous evolution in vitro.

Abstract excerpt

INTRODUCTION: When catalytic RNA is evolved in vitro, the molecule's chemical reactivity is usually the desired selection target. Sometimes the phenotype of a particular RNA molecule cannot be unambiguously determined from its genotype, however. This can occur if a nucleotide sequence can adopt multiple folded states, an example of non-unity heritability (i.e. one genotype gives rise to more than one phenotype)....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Base Sequence
• Share to Evolution, Molecular
• Share to Genotype