Article
The simple emergence of complex molecular function.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences - 11 Jul 2022
Manrubia Susanna
Abstract excerpt
At odds with a traditional view of molecular evolution that seeks a descent-with-modification relationship between functional sequences, new functions can emerge de novo with relative ease. At early times of molecular evolution, random polymers could have sufficed for the appearance of incipient chemical activity, while the cellular environment harbours a myriad of proto-functional molecules. The emergence of...
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