Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation rates and evolution of multiple coding in RNA-based protocells.

Journal of molecular evolution - 1 Dec 2014

de Boer Folkert K, Hogeweg Paulien

Abstract excerpt

RNA has a myriad of biological roles in contemporary life. We use the RNA paradigm for genotype-phenotype mappings to study the evolution of multiple coding in dependence to mutation rates. We study three different one-to-many genotype-phenotype mappings which have the potential to encode the information for multiple functions on a single sequence. These three different maps are (i) cofolding, where two sequences...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cell Membrane
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Molecular Sequence Data

Share to Mutation Rate

Share to Nucleic Acid Conformation

Source

Open in PubMed Open full text

Identifiers

PMID: 25280530
DOI: 10.1007/s00239-014-9648-6
PMCID: PMC4247474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation rates and evolution of multiple coding in RNA-based protocells.PMID 25280530Read ↗

Toward a theory of multilevel evolution: long-term information integration shapes the mutational landscape and enhances evolvability.Semantic proximity Read ↗

Evolution in silico and in vitro: the RNA model.Semantic proximity Read ↗

Modular evolution and increase of functional complexity in replicating RNA molecules.Semantic proximity Read ↗

Mutational robustness accelerates the origin of novel RNA phenotypes through phenotypic plasticity.Semantic proximity Read ↗

Evolution of functional diversification within quasispecies.Semantic proximity Read ↗

Phenotypic error threshold; additivity and epistasis in RNA evolution.Semantic proximity Read ↗

Evolutionary coupling between the deleteriousness of gene mutations and the amount of non-coding sequences.Semantic proximity Read ↗

Evolution of molecular error rates and the consequences for evolvability.Semantic proximity Read ↗

On the evolution of redundancy in genetic codes.Semantic proximity Read ↗

Evolutionary dynamics of RNA-like replicator systems: A bioinformatic approach to the origin of life.Semantic proximity Read ↗

Mistranslation: from adaptations to applications.Semantic proximity Read ↗

Eco-evolutionary dynamics, coding structure and the information threshold.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.