Article
Molecular evolution of catalysis.
Journal of theoretical biology - 7 Aug 2000
Forst C V
Abstract excerpt
In this paper, we consider the evolutionary dynamics of catalytically active species with a distinct genotype-phenotype relationship. Folding landscapes of RNA molecules serve as a paradigm for this relationship with essential neutral properties. The landscape itself is partitioned by phenotypes (realized as RNA secondary structures). To each genotype (represented as a sequence) a structure is assigned in a...
Topics
- Animals
- Catalysis
- Evolution, Molecular
- Genotype
- Models, Genetic
- Neural Networks, Computer
- Phenotype
- RNA