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Article

The suncus (Suncus murinus) shows poor metabolic phenotype for trimethylamine N-oxygenation.

Toxicology and applied pharmacology - 1 Jan 2000

Mushiroda T, Yokoi T, Takahara E, Nagata O, Kato H, Kamataki T

Abstract excerpt

In vitro and in vivo N-oxygenation of trimethylamine (TMA) in the suncus (Suncus murinus) was investigated. The N-oxygenation of TMA has been thought to be catalyzed by flavin-containing monooxygenase (FMO). In a previous study, we found that the levels of mRNAs for FMOs were extremely low in the suncus. Thus, we intended to evaluate the capacity of the suncus to N-oxygenate TMA compared to the rat. Eadie-Hofstee...

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Identifiers

PMID: 10631126
DOI: 10.1006/taap.1999.8820

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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