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Article

Expression and characterization of functional dog flavin-containing monooxygenase 3.

Drug metabolism and disposition: the biological fate of chemicals - 1 Oct 2009

Lickteig Andrew J, Riley Rochelle, Melton Roger J, Reitz Beverly A, Fischer H David, Stevens Jeffrey C

Abstract excerpt

Mammalian flavin-containing monooxygenase (FMO) enzymes catalyze oxidation at nucleophilic, heteroatom centers and are important for drug, xenobiotic, and endogenous substrate metabolism. In human liver, human FMO3 (hFMO3) is the most abundant FMO isoform and is known to contribute to the hepatic clearance of a variety of clinical drugs. The purpose of the current study was to express and compare the dog (beagle)...

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Source

Identifiers

PMID: 19635782
DOI: 10.1124/dmd.109.027714

Genes

FMO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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