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Article

T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell

18 Oct 2010

Abstract excerpt

The conversion of mature somatic cells into pluripotent stem cells, both by nuclear transfer and transduction with specific "reprogramming" genes, represents a major advance in regenerative medicine. Pluripotent stem cell lines can now be generated from an individual's own cells, facilitating the generation of immunologically acceptable stem cell-based therapeutics. Many cell types can undergo nuclear...

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PMID: 20956329
DOI: 10.1073/pnas.1013230107

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