Article
Abnormal bone marrow B-cell differentiation in pre-B lymphoma-prone SL/Kh mice.
Cancer research - 15 Jan 1994
Okamoto K, Yamada Y, Ogawa M S, Toyokuni S, Nakakuki Y, Ikeda H, Yoshida O, Hiai H
Abstract excerpt
SL/Kh mice spontaneously develop pre-B lymphomas with surface phenotypes of B220+, BP-1+, Thy-1-, and surface immunoglobulin negative. The immunoglobulin heavy chain of lymphoma is clonally rearranged but the light chain gene remains in germline configuration. Studying prelymphoma stage SL/Kh bon...
Topics
- Animals
- Bone Marrow
- Cell Differentiation
- Chimera
- Leukemia Virus, Murine
- Lymphoma, B-Cell
- Mice
- Mice, Inbred Strains
- Phenotype
- Precancerous Conditions
