Article
Lymphoid hyperplasia and lymphoma in KSHV K1 transgenic mice.
Histology and histopathology - 1 May 2015
Berkova Zuzana, Wang Shu, Sehgal Lalit, Patel Keyur Pravinchandra, Prakash Om, Samaniego Felipe
Abstract excerpt
Growing evidence supports the involvement of human herpervirus 8, Kaposi's sarcoma associated herpesvirus (KSHV), in the pathology of primary effusion lymphoma, multicentric Castleman's disease, and Kaposi's sarcoma, but the exact mechanism of KSHV contribution to the oncogenic process remains elusive. We studied transgenic mice expressing the ORF K1 of KSHV, whose position in the KSHV genome corresponds to known...
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