Article
Mutations in the gyrA, parC, and parE genes associated with fluoroquinolone resistance in clinical isolates of Mycoplasma hominis.
Antimicrobial agents and chemotherapy - 1 Apr 1999
Bebear C M, Renaudin J, Charron A, Renaudin H, de Barbeyrac B, Schaeverbeke T, Bebear C
Abstract excerpt
Five clinical isolates of Mycoplasma hominis from three different patients were examined for resistance to fluoroquinolones; some of these isolates were probably identical. All five isolates harbored amino acid substitutions in the quinolone resistance-determining regions of both DNA gyrase (GyrA) and topoisomerase IV (ParC or ParE). Furthermore, the novobiocin MIC for three isolates showed a significant...
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