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Article

Insulin but not IGF-I is required for the maintenance of the adipose phenotype in the adipogenic cell line 1246.

In vitro cellular & developmental biology. Animal - 1 Jan 2000

Serrero G, Lepak N

Abstract excerpt

The mouse adipogenic cell line 1246 which possesses both insulin and insulin-like growth factor I (IGF-I) receptors was used to investigate the role of IGF-I and insulin on the proliferation of adipocyte precursors and their differentiation into mature adipocytes. Results indicate that both insulin and IGF-I stimulate the proliferation of the 1246 adipocyte precursors with IGF-I being slightly more potent than...

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Source

Identifiers

PMID: 10614875
DOI: 10.1007/s11626-999-0104-7

Genes

LPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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