Article
Characterisation of insulin-resistant phenotype of cultured rat primary adipose cells.
Diabetologia - 1 May 2007
Xiang C C, Wu Y J, Ma L, Ding L, Lisinski I, Brownstein M J, Cushman S W, Chen X
Abstract excerpt
AIMS/HYPOTHESIS: We characterised insulin resistance, metabolic defects and endocrine dysfunction in cultured adipose cells and examined the autocrine or paracrine roles of cytokines/adipokines in the progression of insulin resistance. MATERIALS AND METHODS: Rat primary adipose cells were prepared and cultured for 24 and 48 h. Insulin resistance and gene expression were examined by glucose uptake assay, cDNA...
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