Enhancement of adipocyte differentiation by an insulin-sensitizing agent.

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Article

Enhancement of adipocyte differentiation by an insulin-sensitizing agent.

Molecular pharmacology - 1 Feb 1992

Kletzien R F, Clarke S D, Ulrich R G

Abstract excerpt

The thiazolidinediones are a class of novel antidiabetic compounds that enhance the response of target tissues to insulin. Pioglitazone, a thiazolidinedione analog, lowers blood glucose and insulin levels in rodent models of non-insulin-dependent diabetes mellitus. We have studied the effect of p...

Topics

3T3 Cells
Adipose Tissue
Animals
Cell Differentiation
Cells, Cultured
Glucosephosphate Dehydrogenase
Hypoglycemic Agents
Insulin
Insulin-Like Growth Factor I
Lipids
Lipoprotein Lipase
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Monosaccharide Transport Proteins

Phenotype

Pioglitazone

RNA, Messenger

Thiazoles

Thiazolidinediones

Source

Open in PubMed

Identifiers

PMID: 1538716

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1538716-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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