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Article

Enhancement of adipocyte differentiation by an insulin-sensitizing agent.

Molecular pharmacology - 1 Feb 1992

Kletzien R F, Clarke S D, Ulrich R G

Abstract excerpt

The thiazolidinediones are a class of novel antidiabetic compounds that enhance the response of target tissues to insulin. Pioglitazone, a thiazolidinedione analog, lowers blood glucose and insulin levels in rodent models of non-insulin-dependent diabetes mellitus. We have studied the effect of pioglitazone on 3T3-L1 cells, a cell line that undergoes differentiation from a preadipocyte fibroblastic morphology to...

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PMID: 1538716

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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