Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Strain-specific white-spotting patterns in laboratory mice.

Pigment cell research - 1 Dec 1999

Lamoreux M L

Abstract excerpt

White spotting is the absence of melanocytes (pigment cells) from part or all of the locations in the body where they are normally found. At least in the case of the W (kit) locus, white spotting has been attributed to apoptosis. In addition to the death of melanoblasts, white spotting might result from their failure to migrate to their normal locations. These developmental failures are known to be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to KIT gene
Share to Melanocytes
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Mice, Inbred Strains

Share to Phenotype

Share to Skin Pigmentation

Source

Identifiers

PMID: 10614578
DOI: 10.1111/j.1600-0749.1999.tb00522.x

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Strain-specific white-spotting patterns in laboratory mice.PMID 10614578Read ↗

Spotlight on spotted mice: a review of white spotting mouse mutants and associated human pigmentation disorders.Semantic proximity Read ↗

Long-range genomic rearrangements upstream of Kit dysregulate the developmental pattern of Kit expression in W57 and Wbanded mice and interfere with distinct steps in melanocyte development.Semantic proximity Read ↗

Inheritance of white spotting in mice.Semantic proximity Read ↗

White spotting allele alters color of yellow mice.Semantic proximity Read ↗

Quantitative trait loci that modify the severity of spotting in piebald mice.Semantic proximity Read ↗

The Wsh and Ph mutations affect the c-kit expression profile: c-kit misexpression in embryogenesis impairs melanogenesis in Wsh and Ph mutant mice.Semantic proximity Read ↗

Regional Fluctuation in the Functional Consequence of LINE-1 Insertion in the Mitf Gene: The Black Spotting Phenotype Arisen from the Mitfmi-bw Mouse Lacking Melanocytes.Semantic proximity Read ↗

The color loci of mice--a genetic century.Semantic proximity Read ↗

Ectopic expression of a c-kitW42 minigene in transgenic mice: recapitulation of W phenotypes and evidence for c-kit function in melanoblast progenitors.Semantic proximity Read ↗

Mice transgenic for Kit(V620A): recapitulation of piebaldism but not progressive depigmentation seen in humans with this mutation.Semantic proximity Read ↗

Conditional Deletion of Kit in Melanocytes: White Spotting Phenotype Is Cell Autonomous.Semantic proximity Read ↗

The Tyr (albino) locus of the laboratory mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.