Article
High albumin production by multicellular spheroids of adult rat hepatocytes formed in the pores of polyurethane foam.
Applied microbiology and biotechnology - 1 Dec 1991
Matsushita T, Ijima H, Koide N, Funatsu K
Abstract excerpt
Adult rat hepatocytes formed spherical multicellular aggregates (spheroids) when they were cultured in the pores of polyurethane foam (PUF). The diameter of the spheroids was within the range 100-200 microns. These spheroids partly attached and immobilized in the PUF pores for at least 2 weeks. The albumin production rate by the spheroids increased up to 17.0 micrograms/10(6) nuclei per day during the first 6...
Topics
- Albumins
- Animals
- Cells, Cultured
- Liver
- Phenotype
- Polyurethanes
- Rats
- Rats, Inbred Strains