Article
Folate status and neural tube defects.
BioFactors (Oxford, England) - 1 Jan 1999
Molloy A M, Mills J L, Kirke P N, Weir D G, Scott J M
Abstract excerpt
Periconceptional folic acid supplementation prevents approximately 70% of neural tube defects (NTDs). While most women carrying affected fetuses do not have deficient blood folate levels, the risk of having an NTD affected child is inversely correlated with pregnancy red cell folate levels. Current research is focused on the discovery of genetic abnormalities in folate related enzymes which might explain the role...
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