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Article

Evaluation of genetic variation and association in the matrix metalloproteinase 9 (MMP9) gene in ESRD patients.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Jul 2003

Hirakawa Shohei, Lange Ethan M, Colicigno Carla J, Freedman Barry I, Rich Stephen S, Bowden Donald W

Abstract excerpt

BACKGROUND: Matrix metalloproteinases are Zn2+- and Ca2+-dependent endopeptidases secreted by many cells. Expression of the matrix metalloproteinase 9 (MMP9) gene is increased in a variety of renal diseases. Several genetic studies have associated MMP9 with end-stage renal disease (ESRD). METHODS: In this study, 2.2 kb of the promoter region and all 13 exons (3.3 kb) of MMP9 genomic DNA were scanned for...

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Identifiers

PMID: 12830465
DOI: 10.1016/s0272-6386(03)00416-5

Genes

MMP9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evaluation of genetic variation and association in the matrix metalloproteinase 9 (MMP9) gene in ESRD patients.PMID 12830465Read ↗

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