Article
Evaluation of genetic variation and association in the matrix metalloproteinase 9 (MMP9) gene in ESRD patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Jul 2003
Hirakawa Shohei, Lange Ethan M, Colicigno Carla J, Freedman Barry I, Rich Stephen S, Bowden Donald W
Abstract excerpt
BACKGROUND: Matrix metalloproteinases are Zn2+- and Ca2+-dependent endopeptidases secreted by many cells. Expression of the matrix metalloproteinase 9 (MMP9) gene is increased in a variety of renal diseases. Several genetic studies have associated MMP9 with end-stage renal disease (ESRD). METHODS...
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