Article
Mapping of a gene predisposing to familial thyroid tumors with cell oxyphilia to chromosome 19 and exclusion of JUN B as a candidate gene.
Surgery - 1 Dec 1999
Kraimps J L, Canzian F, Jost C, Menet E, Amati P, Levillian P, Harach R, Lesueur F, Barbier J, Romeo G, Bonneau D
Abstract excerpt
BACKGROUND: Familial nonmedullary thyroid carcinoma (FNMTC) is a clinical entity characterized by a more aggressive phenotype than the sporadic counterpart. The transmission of susceptibility of FNMTC is compatible with autosomal dominant inheritance. We report the identification of a new entity of FNMTC and the mapping of the responsible gene named TCO (for thyroid tumor with cell oxyphilia). METHODS: In one...
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